Perioperative Factors and Living Donor Liver Transplantation

Min Suk Chae

Status: Not yet enrolling

Conditions: Liver Transplant Disorder

Treatments: Other: remote ischemic preconditioning (RIPC)

Study type: Observational

Funder types: Other

Identifiers

NCT06312098

KC21RISI0576

Details and patient eligibility

About

Liver transplant surgery is one of the treatments provided to patients suffering from end-stage liver disease, and has a successful treatment prognosis. However, it is clear that patient management before, during, and after surgery is a difficult task for medical staff due to the complex clinical and pathological problems of end-stage liver disease. Moreover, the complex surgical technique of the liver transplant surgery itself and the severe hemodynamic fluctuations and multi-organ dysfunction that patients experience during the surgery have been shown to have a tremendous impact on the patient's prognosis after surgery.

A study on which clinical, laboratory, and hemodynamic factors experienced by patients during the perioperative period, including before, during, and after surgery, affect the survival rate of patients and transplanted organs. will definitely be helpful in the treatment of patients suffering from end-stage liver disease.

Enrollment: 533 estimated patients

Sex: All

Ages: 19 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adults
• elective surgery
• American Society of Anesthesiologists (ASA) physical status classification system I, II, III

Exclusion criteria

• American Society of Anesthesiologists (ASA) physical status classification system IV, V

Trial design

533 participants in 2 patient groups

no-remote ischemic preconditioning group

Description:

patients who did not receive remote ischemic preconditioning

paired remote ischemic preconditioning group

Description:

patients who receive remote ischemic preconditioning

Treatment:

Other: remote ischemic preconditioning (RIPC)