Perioperative Outcome of Corticosteroids in Transforaminal Endoscopic Lumbar Discectomy

Mahidol University

Status and phase: Completed; Phase 4

Conditions: Lumbar Disc Herniation

Treatments: Drug: Placebos; Drug: 40 mg Triamcinolone acetate 1 cc

Study type: Interventional

Funder types: Other

Identifiers

NCT03273036

ID 03-54-23

Details and patient eligibility

About

The endoscopic discectomy has rapidly developed and increased need by patients. This procedure is widely performed by interventional pain physicians as well as by spine surgeons because it requires no general anesthesia or admission to a hospital. Many studies were reported that corticosteroid injection can inhibit persistent postoperative pain in lumbar discectomy. However, data of perioperative epidural steroids after an endoscopic discectomy is lacking.

Full description

To examine whether corticosteroid administered epidural space in patients undergoing endoscopic lumbar discectomy reduces postoperative morphine consumption, back and leg pain relief, improves functional disability comparing to placebo

Enrollment: 30 patients

Sex: All

Ages: 20 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Lumbar disc herniation patient age 20-45 year-old who have symptom duration was at least 6 weeks and conservative treatment failed

Exclusion criteria

• Refuse to participate and inform consent, Previous spinal surgery, History of allergic to steroid

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

epidural steroid injection

Active Comparator group

Description:

40 mg triamcinolone acetate 1 cc

Treatment:

Drug: 40 mg Triamcinolone acetate 1 cc

placebo injection

Placebo Comparator group

Description:

no injection agent

Treatment:

Drug: Placebos