Renal Stone Treatment Global Registry

The Chinese University of Hong Kong

Status: Enrolling

Conditions: Urolithiasis

Study type: Observational

Funder types: Other

Identifiers

NCT05297331

CRE-2021.684

Details and patient eligibility

About

This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.

Full description

Renal stone is a common condition, and many patients suffered from recurrent diseases and required multiple interventions in their lifetime. Currently, there are many treatment options available for stone treatment, including shockwave lithotripsy, ureteroscopy, percutaneous nephrolithotomy etc.

Different treatment approaches will result in different treatment successful rate and also potential adverse effects to patients. The main challenge for stone management is the decision on the best treatment approach for individual stone of each patient. This is because for the same type of stone (such as lower caliceal stone or upper ureteric stone), different surgical treatment could be applied. The decision will depend on various patients (such as age, premorbid etc.) and stone factors (such as size, density etc) and also patients' preference.

New advances in technology have improved treatment outcomes for urolithiasis, such as single use flexible ureteroscopes, flexible and navigable ureteral access sheaths (FANS), direct in scope suction (DISS), intrarenal pressure (IRP) and intrarenal temperature (IRT) monitoring devices, new lasers and pulse modulation, etc.

Therefore, in order to have more information to guide treatment decision during discussion with patients, a prospective data registry is created to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters. This information will be important for audit, treatment comparison and also patient education.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient at the age of 18 or above

Exclusion criteria

• Patient is unable to give consent

Trial design

3,000 participants in 5 patient groups

FLEXOR-FANS (flexible and navigable suction ureteral access sheath)

Description:

Cohort of flexible ureteroscopy with flexible and navigable suction ureteral access sheath (fURS FANS) will be studied

DISS (Direct in scope suction)

Description:

Cohort of flexible ureteroscopy with direct in scope suction (DISS) will be studied

Flexible ureteroscopy - IRP / IRT

Description:

Cohort of flexible ureteroscopy with and without real-time intrarenal pressure (IRP) monitoring and/or intrarenal temperature (IRT) will be studied

Shockwave lithotripsy (SWL)

Description:

Cohort of extracorporeal shockwave lithotripsy (SWL) will be studied

Percutaneous nephrolithotomy (PCNL)

Description:

Cohort of percutaneous nephrolithotomy with or without intrarenal pressure and temperature monitoring will be studied.