Perioperative Respiratory Adverse events_sugammadex

Seoul National University

Status and phase: Completed; Phase 4

Conditions: Respiratory Complication

Treatments: Drug: Neostigmine; Drug: Sugammadex injection

Study type: Interventional

Funder types: Other

Identifiers

NCT05354466

2203-061-1305

Details and patient eligibility

About

Perioperative respiratory adverse events are common in children. We aimed to evaluate the effect of sugammadex on the incidence of perioperative respiratory adverse events in pediatric patients receiving tonsillectomy

Enrollment: 174 patients

Sex: All

Ages: 2 to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pediatric patients aged 2-6 years who were scheduled for tonsillectomy under general anesthesia were enrolled

Exclusion criteria

• a recent history of upper respiratory tract infection within 2 weeks of surgery
• allergic reaction to sugammadex
• renal failure
• liver failure
• arrhythmia

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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174 participants in 2 patient groups

Sugammadex as reversal agent

Experimental group

Treatment:

Drug: Sugammadex injection

Neostigmine as reversal agent

Active Comparator group

Treatment:

Drug: Neostigmine