Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic

aijun xu

Status: Completed

Conditions: Postoperative Complications; Elective Non-cardiac Surgery; Perioperative Respiratory Adverse Events; URTI; COVID - 19

Study type: Observational

Funder types: Other

Identifiers

NCT07157111

PPOC

Details and patient eligibility

About

The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The main question it aims to answer is the appropriate timing of elective non-cardiac surgery in the post-COVID-19 era.

Full description

This study aims to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The findings will provide evidence-based guidance for optimizing surgical timing decisions in the post-COVID-19 era.

Enrollment: 2,392 patients

Sex: All

Ages: 1 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 0-12 years
• ASA physical status classification I-III
• Undergoing non-cardiac surgery
• Children presenting with mild URTI symptoms within 2 weeks before surgery

Exclusion criteria

• Presenting with severe underlying diseases (e.g., congenital heart disease, immunodeficiency)
• Presenting with a single symptom of fever that can be explained by other diseases
• Day surgery
• Children with abnormal preoperative chest X-rays

Trial design

2,392 participants in 4 patient groups

S1 group

Description:

children with preoperative upper respiratory tract infections symptoms undergoing elective non-cardiac surgery from January 1, 2015, to December 31, 2019

C1 group

Description:

children without preoperative upper respiratory tract infections undergoing elective non-cardiac surgery from January 1, 2015, to December 31, 2019

S2 group

Description:

children with preoperative upper respiratory tract infections symptoms undergoing elective non-cardiac surgery from January 1, 2020, to December 31, 2024

C2 group

Description:

children without preoperative upper respiratory tract infections symptoms undergoing elective non-cardiac surgery from January 1, 2020, to December 31, 2024