Peripheral Metabolic Effects of Ghrelin

University of Aarhus

Status and phase: Completed; Phase 1

Conditions: Healthy Controls

Treatments: Drug: Ghrelin

Study type: Interventional

Funder types: Other

Identifiers

NCT00771940

M-2007008

Details and patient eligibility

About

The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.

Enrollment: 8 estimated patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. BMI < 27 kg/m2
2. Written informed consent
3. Non-smoker

Exclusion criteria

1. Any disease including epilepsy
2. Any use of medications (excl. paracetamol)
3. Present or previous malignancy
4. Alcohol dependency
5. Allergy to any trial medication

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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8 participants in 1 patient group

Ghrelin

Active Comparator group

Treatment:

Drug: Ghrelin