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Peripheral Metabolic Effects of Somatostatin

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University of Aarhus

Status

Completed

Conditions

Diabetes
Acromegaly
Growth Hormone Deficiency

Treatments

Drug: Somatostatin

Study type

Interventional

Funder types

Other

Identifiers

NCT01062529
M-2008005

Details and patient eligibility

About

The aim of this study is to investigate peripheral effects of Somatostatin on glucose metabolism and growth hormone (GH) signalling in healthy men. Eight subjects will be enrolled. The hypothesis is that Somatostatin infusion reverses insulin resistance caused by GH.

Enrollment

8 patients

Sex

Male

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • BMI < 27 kg/m2
  • Written informed consent
  • Healthy

Exclusion criteria

  • Any disease
  • Any use of medications
  • Present or previous malignancy
  • Alcohol dependency
  • Allergy to trial medication

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Single Group Assignment

Masking

Single Blind

8 participants in 1 patient group

somatostatin
Experimental group
Treatment:
Drug: Somatostatin

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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