Peripheral Metabolic Effects of Somatostatin

University of Aarhus

Status: Completed

Conditions: Diabetes; Acromegaly; Growth Hormone Deficiency

Treatments: Drug: Somatostatin

Study type: Interventional

Funder types: Other

Identifiers

NCT01062529

M-2008005

Details and patient eligibility

About

The aim of this study is to investigate peripheral effects of Somatostatin on glucose metabolism and growth hormone (GH) signalling in healthy men. Eight subjects will be enrolled. The hypothesis is that Somatostatin infusion reverses insulin resistance caused by GH.

Enrollment: 8 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI < 27 kg/m2
• Written informed consent
• Healthy

Exclusion criteria

• Any disease
• Any use of medications
• Present or previous malignancy
• Alcohol dependency
• Allergy to trial medication

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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8 participants in 1 patient group

somatostatin

Experimental group

Treatment:

Drug: Somatostatin