Peripheral Nerve Activation Sensitivity (PERNEAC)

Thomas Niederhauser

Status

Enrolling

Conditions

Nerve Excitation Sensitivity

Treatments

Device: Electric and electromagnetic stimulation

Study type

Interventional

Funder types

Other

NETWORK

Identifiers

NCT07160413

108.018 IP-LS (Other Grant/Funding Number)

2025-00776

Details and patient eligibility

About

Volunteers will undergo various peripheral nerve stimulations (electric, electromagnetic, and temporal interference) to evaluate each method's sensitivity. The main objective is to examine the relationship between nerve activation and coil placement relative to the nerve, as well as how different coil types influence maximal nerve activation.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Person aged > 18 years
Signed informed consent
Healthy
Willingness and ability to adhere to study procedures

Exclusion criteria

Known hypersensitivity to electric or electromagnetic stimulation
Any implanted metal or electronic device in the upper body (except dental work such as fillings or braces), e.g., active medical devices, metal implants
Neurological or neuromuscular disorders or conditions
History of seizures or epilepsy
Current treatment with drugs that lower seizure threshold (e.g., certain analgesics, methylxanthines, antipsychotics, antidepressants, antiepileptics, anesthetics)
Pregnancy or breastfeeding
Surgical intervention of the arm within the last 4 weeks
Allergy to adhesives or ultrasound gel components (e.g., polyethylene glycols)
Skin lesions, infections, or strictures in the arm region
Tattoos on the stimulated (right) arm and hand, or in any area likely to be captured in video recordings
Inability to follow study procedures (e.g., due to language barrier, psychological disorders, dementia)
Participant deprived of liberty by administrative or judicial decision or under legal guardianship