Peripherel Perfusion Index to Predict Sepsis in Very Low Birth Weight Infants

Fudan University

Status: Completed

Conditions: VLBW - Very Low Birth Weight Infant

Treatments: Other: Not applicable (cohort study)

Study type: Observational

Funder types: Other

Identifiers

NCT05224921

2021-454

Details and patient eligibility

About

To explore the predictive value of peripheral perfusion index in late onset sepsis of very low birth weight infants , obtain the threshold by observing the perfusion index of very low birth-weight infants within one month after birth, this value can be used as a threshold to predict late onset sepsis in very low birth weight infants.

Full description

From the day the very low birth weight infant was admitted to hospital, monitoring was recorded once a day, and continuous monitoring was recorded for 1 month. Before collection, the infant was confirmed to be in supine position with neutral temperature, and at the same time, the infant was in a quiet state, without the contact and operation of medical personnel. This study will first use LMS curve to fit the trend of perfusion index in very low birth weight infants within one month after birth.The perfusion index threshold of the outcome index was determined by ROC curve.

Enrollment: 216 patients

Sex: All

Ages: Under 3 days old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Infants weighting <1500g
• Infants admitted to Children's Hospital of Fudan University

Trial design

216 participants in 1 patient group

Very low birth weight infants

Description:

Include very low birth weight infants admitted into NICU in Children's hospital of Fudan University, and prospectively observe whether they get late onset sepsis.

Treatment:

Other: Not applicable (cohort study)