Peritoneal Closure Versus Non Closure During Open Appendectomy

Bezmialem Vakif University

Status: Completed

Conditions: Acute Appendicitis

Treatments: Procedure: open appendectomy with peritoneal closure; Procedure: open appendectomy without peritoneal closure

Study type: Interventional

Funder types: Other

Identifiers

NCT02803463

16_12_2015-23/14

Details and patient eligibility

About

There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.

Full description

There has been no consensus over closure versus non closure of peritoneum during abdominal operations. in literature, few reports suggested that peritoneal closure may prolong the operation time, may increase the costs and has a probable aggravating effect on postoperative pain. In addition, there have been some reports that suggest non closure of peritoneum may not increase the postoperative complications. The need of further studies to clarify the effect of peritoneal closure versus non closure on postoperative pain and life quality especially has been specified in some literature. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.

Enrollment: 112 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with acute appendicitis
• age between 18-65 years

Exclusion criteria

• preoperatively diagnosed intraabdominal abcess
• intraoperatively diagnosed free purulent fluid in abdominal cavity
• pregnancy
• malignancy history
• mental retardation
• chronical renal failure
• chronical liver disease
• diabetes mellitus
• patients' denial of participation to study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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112 participants in 2 patient groups

Peritoneal Closure

Active Comparator group

Description:

open appendectomy with peritoneal closure

Treatment:

Procedure: open appendectomy with peritoneal closure

Peritoneal Non Closure

Active Comparator group

Description:

open appendectomy without peritoneal closure

Treatment:

Procedure: open appendectomy without peritoneal closure