Peritoneal Dialysis Daily Versus Six Days Per Week
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Details and patient eligibility
About
The study will enroll patients receiving daily peritoneal dialysis who have significant residual native kidney function. The investiators will visit the patients at a routinely scheduled clinic visit and again at a non-routine visit after the patients skip a single day of dialysis. Blood samples will be obtained and a quality of life questionnaire will be administered at both visits.
The primary aim will be to determine whether the patients would prefer daily treatment or being allowed to skip one day per week.
Other aims will be to determine the effect of skipping a day on plasma levels of urea nitrogen and creatinine.
Full description
The patients' preference will be assessed by asking the simple question would you prefer to perform peritoneal dialysis daily of six days per week.
The quality of life questionnaire to be used will be the Dialysis Symptom Index (DSI) which has a range of 0 to 150 with a high score reflecting worse quality of life.
The chemical to be measured will be the plasma urea nitrogen in mg/dl and the plasma creatinine in mg/dl as measured by the clinical laboratory.
Sex
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Volunteers
Inclusion criteria
- Daily treament with peritoneal dialysis and residual native kidney funciton with residual urea clearance greater than 2 ml/min.
Exclusion criteria
- less than 3 months on peritoneal dialysis
- recent change in the dialysis prescriptoin
- recent peritonitis
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 1 patient group
Trial contacts and locations
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Central trial contact
Timothy W Meyer, MD
Data sourced from clinicaltrials.gov
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