Peroperative Use of Positive End-expiratory Pressure Prevents Formation of Atelectasis as Studied by Computerised Tomography at End of Surgery

Region Västmanland

Status

Completed

Conditions

Atelectasis

Treatments

Procedure: Control group, zero PEEP

Procedure: Positive end-expiratory pressure

Study type

Interventional

Funder types

Other

Identifiers

NCT02548416

Dnr 2015/338

Details and patient eligibility

About

Atelectasis is common during and after general anaesthesia and a number of interventions have been suggested in order to prevent their formation. The use of Positive End Expiratory Pressure (PEEP) during general anaesthesia has in recent years been questioned.

The investigators hypothesize that the use of PEEP as a single intervention improves oxygenation and prevents atelectasis as investigated by computed tomography compared to a control group with zero PEEP.

Enrollment

24 patients

Sex

All

Ages

40 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Healthy subjects, American Society of Anesthesiology (ASA) I-II.
Patients scheduled for non-abdominal day case surgery under general anaesthesia.

Exclusion criteria

ASA class III or higher.
Body Mass Index (BMI) 30 or higher.
Arterial oxygen saturation (SpO2) <96% breathing air.
Chronic Obstructive Pulmonary Disease (COPD).
Ischaemic heart disease.
Known or anticipated difficult airway.
Active smokers and ex-smokers with a history of more than 6 pack years.
Need for interscalene or supraclavicular plexus block for postoperative pain relief (risk of phrenic nerve paralysis).