Personalized Computerized Inhibitory Control Training for OCD

New York State Psychiatric Institute

Status: Completed

Conditions: Obsessive-Compulsive Disorder

Treatments: Behavioral: Personalized Computer Program; Behavioral: Cognitive Behavioral Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02378896

#7059

Details and patient eligibility

About

This study will evaluate the effects of a computerized training program coupled with cognitive behavioral therapy (CBT) for OCD.

Full description

This study will evaluate the effectiveness of a computerized training program (called Personalized Computerized Inhibitory Training, or PCIT) coupled with cognitive behavioral therapies (CBT) consisting of Exposures and Response Prevention in treating obsessive compulsive disorder (OCD) in patients who previously underwent CBT, but still have residual symptoms.

Enrollment: 11 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Principal diagnosis of OCD (assessed by SCID).
• Clinically significant OCD symptoms (Y-BOCS score of at least 16).
• Have a history of completing a trial of at least 1 EX/RP sessions.
• Have access to a computer or laptop.

Exclusion criteria

• Individuals with the following disorders will excluded: bipolar, psychosis, current major depressive disorder (assessed by SCID).
• Patients with head injury and loss of consciousness of more than five minutes or a neurological condition affecting the central nervous system.
• Patients taking a psychiatric medication will be asked to maintain a stable dose for 6 weeks prior to study entry.
• Vision or hearing loss (although individuals with vision corrected by glasses or contacts will not be excluded).
• Active suicidality warranting immediate clinical care.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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11 participants in 1 patient group

CBT + Personalized Computer Program

Experimental group

Description:

Cognitive Behavioral Therapy (CBT), consisting of Exposure and Ritual Prevention Therapy and training with a personalized computerized inhibitory training program

Treatment:

Behavioral: Personalized Computer Program

Behavioral: Cognitive Behavioral Therapy