Personalized Inhibitory Control Training for Compulsive Behavior Change

Hebrew University of Jerusalem

Status: Unknown

Conditions: OCD

Treatments: Behavioral: Placebo; Behavioral: P-CIT protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT03682913

0105-18-HMO

Details and patient eligibility

About

Obsessive-compulsive disorder (OCD) is a severe mental illness characterized by repetitive behaviors that a person feels compelled to perform. It has been demonstrated that stimuli in the environment can trigger the compulsive urge, perpetuating the OCD cycle. The main goal of the current proposal, which is based on exciting pilot data, is to test a novel computerized training program to create an association between OCD-related stimuli, which typically trigger the compulsive urge, and the brain system responsible for stopping. The idea is that once this system is triggered, it will be easier for patients to stop the compulsive urge.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• OCD patients

Exclusion criteria

• Metal/ electronic device
• Under the age of 18
• Pregnant women
• Tattoos that cover over 10% of body mass
• Chronically ill patients
• Psychosis/ Bi-polar
• Substance abuse
• Sever depression
• Active suicide thoughts
• Hearing loss

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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50 participants in 2 patient groups, including a placebo group

P-CIT protocol

Experimental group

Description:

OCD patients who receive the P-CIT intervention.

Treatment:

Behavioral: P-CIT protocol

Placebo

Placebo Comparator group

Description:

OCD patients who don't receive the P-CIT intervention.

Treatment:

Behavioral: Placebo