Perspective Analysis of Coronal Imbalance in Degenerative Scoliosis

Nanjing University School of Medicine

Status: Completed

Conditions: Scoliosis

Treatments: Procedure: Posterior osteotomy correction

Study type: Observational

Funder types: Other

Identifiers

NCT02388555

2013-079-01

Details and patient eligibility

About

Currently there is paucity of information on the prevalence of pre-operative coronal imbalance in patients with degenerative lumbar scoliosis (DLS) and its influence on surgical outcomes. This study aims to investigate in DLS, the prevalence of coronal imbalance, to propose a novel classification system and to investigate whether pre-operative coronal imbalance affects clinical outcomes following osteotomy. A total of 284 DLS patients were recruited.

Full description

A total of 284 DLS patients were recruited into this two-stage study, among which 69 patients were treated by posterior-only correction and the remaining 215 patients received conservative treatment. Using pre-operative long-cassette X-ray films, all patients were classified based on coronal balance distance (CBD) defined as the horizontal distance between C7 plumb line and central sacral vertical line: Type A, CBD < 3cm; Type B, CBD > 3cm and C7PL shifts to the concave side of curve; Type C, CBD > 3cm and C7PL shifts to the convex side of curve. The prevalence of pre-operative coronal imbalance was calculated for stage I study. Post-operative CBD in patients who received surgery was measured to evaluate clinical outcomes for stage II study.

Enrollment: 284 patients

Sex: All

Ages: 50 to 82 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

age > 50 years, diagnosis of DLS based on radiographies and previous medical history and Cobb angle >25°.

Exclusion criteria

Trial design

284 participants in 2 patient groups

Pre-operative group

Description:

Respectively recruited patients with DLS. Patients in this group were not surgically treatment. Only pre-operative radiographic parameters were measured.

Surgically treated group

Description:

All DLS patients received posterior osteotomy correction of spinal deformity. The immediate post-operative radiographic measurements were performed.

Treatment:

Procedure: Posterior osteotomy correction