PET-CT Imaging With PCD-CT
Status
Suspended
Conditions
Head and Neck Cancer (H&N)
Treatments
Other: PCD-CT
Other: PET CT
Details and patient eligibility
About
This pilot study evaluates the clinical utility of photon counting detector computed tomography (PCD-CT) in PET-CT imaging for head and neck cancer. Twenty adult patients undergoing standard-of-care PET-CT will also receive PCD-CT imaging. The study compares image quality and diagnostic confidence between conventional energy-integrating detector CT (EID-CT) and PCD-CT for attenuation correction and anatomical imaging.
Enrollment
20 estimated patients
Sex
All
Ages
18+ years old
Volunteers
No Healthy Volunteers
Inclusion criteria
- Age ≥ 18 years
- Scheduled for or completed standard-of-care PET-CT of head and neck within ≤30 days
Exclusion criteria
- Non-diagnostic PET-CT
- Intervening therapy between scans
- Iodinated contrast allergy
- Renal insufficiency (GFR < 45)
- Pregnancy
- Gross motion artifacts
Trial design
Primary purpose
Other
Allocation
Non-Randomized
Interventional model
Single Group Assignment
Masking
Single Blind
20 participants in 2 patient groups
PET CT scan
Other group
Description:
To compare the image quality of PET images constructed using non-contrast PCD-CT image data to PET images constructed using conventional standard-of-care non-contrast EID-CT image data by performing a quantitative analysis of measurable image quality parameters.
Treatment:
Other: PCD-CT
PCD-CT
Other group
Description:
To compare the subjective image quality of PET images constructed using non-contrast PCD-CT image data to PET images constructed using conventional standard-of-care non-contrast EID-CT image data by performing a qualitative analysis of diagnostic confidence as determined by board-certified radiologists/nuclear medicine physicians during image review.
Treatment:
Other: PET CT
Trial contacts and locations
1
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Data sourced from clinicaltrials.gov
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