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This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.
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This cross-sectional study involves both retrospective and prospective data collection from elderly lymphoma patients (aged 60 years or older) at the Nuclear Medicine Unit, South Egypt Cancer Institute. It evaluates the PET-CT imaging findings alongside metabolic parameters such as Standardized Uptake Value (SUV), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG). The study addresses diagnostic challenges in elderly patients due to atypical presentations and comorbidities and fills the gap of scarce local data in Egypt. Imaging analysis includes visual and semiquantitative assessment of lymphatic and extranodal lesions post-injection of 18F-FDG, assessing tumor metabolic activity to provide prognostic insights. Data analysis uses SPSS with relevant statistical tests to validate findings.
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Inclusion criteria
- Age ≥ 60 years
Histopathological diagnosis of lymphoma
Exclusion criteria
- Presence of other concurrent active malignancies
Uncontrolled diabetes mellitus with blood glucose > 200 mg/dL at the time of PET/CT scan
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Data sourced from clinicaltrials.gov
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