PET-MRI Esophagus Feasibility Study

University Health Network, Toronto

Status: Enrolling

Conditions: Esophagogastric Cancer

Treatments: Procedure: PET-MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT05796102

22-5780

Details and patient eligibility

About

This is a single arm, single centre, investigator initiated study to investigate the feasibility of using PET-MRI imaging in radiation treatment workflow in up to 15 patients with esophagogastric cancer. PET-MRI imaging will be completed before the start of radiation treatment. MRI imaging will be completed during radiation treatment and after radiation treatment. These images will not be used to plan the radiation treatment and routine clinical care will be provided.

The goal of this study is to gather information that will allow the radiation team to include MRI and PET imaging into the radiation treatment workflow for patients with esophageal cancer receiving radiation therapy in the future.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 18 years or older
• Diagnosed with locally advanced esophageal cancer being considered for conventional RT >4 weeks
• Ability and willingness to provide written informed consent

Exclusion criteria

• Contraindication for MRI
• Contraindication for Gadolinium (i.e. inability to lie supine for at least 60 minutes)
• Any patient who is pregnant or breastfeeding
• Pacemaker or implanted defibrillator
• Claustrophobia

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

PET-MRI

Experimental group

Description:

PET-MRI in esophagogastric cancers

Treatment:

Procedure: PET-MRI