PET Scan as a Screening Tool for Liver Transplant in Patients With Hepatocellular Carcinoma (HCC)

McGill University

Status: Completed

Conditions: Hepatocellular Carcinoma

Treatments: Other: PET Scan

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01320852

BMD-09-209

Details and patient eligibility

About

This study aims at testing the utility of PET Scan as a screening tool for liver transplantation in patients with Hepatocellular Carcinoma. Patients being worked up for liver transplant for hepatocellular carcinoma will undergo a PET Scan and will be followed until 2 years after transplantation. At that time survival data will be analysed according to PET Scan results to determine if it can be used to predict outcome.

Enrollment: 100 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female patient over 18 years of age
• Diagnosis of HCC confirmed by histology if available or by two imaging modalities
• Able to give written informed consent prior to any study specific screening procedures with the understanding that the patient has the right to withdraw from the study at any time, without prejudice.

Exclusion criteria

• Unable to give consent to the study
• Unable to undergo a PET Scan

Trial design

100 participants in 2 patient groups

Milan Criteria

Active Comparator group

Description:

Patients meeting the Milan Criteria

Treatment:

Other: PET Scan

No Milan Criteria

Other group

Description:

Patients not meeting the Milan Criteria

Treatment:

Other: PET Scan