PG Versus TG for Advanced PGC

National Taiwan University

Status: Active, not recruiting

Conditions: Gastrectomy; Gastric Adenocarcinoma

Treatments: Procedure: total gastrectomy; Procedure: proximal gastrectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT06614439

202408135RIND

Details and patient eligibility

About

We conducted a retrospective study on patients with pathological stage II-III PGC who underwent PG or TG from 2013 to 2023. Propensity score-matching was applied to adjust for tumor size and stage between the PG and TG groups at a 1:1 ratio. We evaluated the procedural safety, oncological, and functional outcomes.

Enrollment: 96 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Proximal gastric adenocarcinoma after total or proximal gastrectomy.

Exclusion criteria

• Non-curative resections
• Non-adenocarcinoma histology
• Distally located tumors or middle/proximally located tumors for which distal margin could not be secured by PG
• Remnant gastric cancer
• Clinically T1N0 tumors smaller than 3 cm for which PG was clearly indicated

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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96 participants in 2 patient groups

Proximal gastrectomy

Experimental group

Treatment:

Procedure: proximal gastrectomy

Total gastrectomy

Active Comparator group

Treatment:

Procedure: total gastrectomy