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PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers

D

Danish Headache Center

Status and phase

Terminated
Phase 1

Conditions

Migraine
Headache

Treatments

Drug: PGI2

Study type

Interventional

Funder types

Other

Identifiers

NCT00291395
KA05055

Details and patient eligibility

About

Before , during and after intravenous administration of PGI2 we score/measure headache, rCBF, blood flow in middle cerebral artery and diameter of superficial temporal artery/radial artery and correlate that to known patophysiology of headache to see if PGI2 is involved in headache pathophysiology.

Sex

All

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy volunteers,

Exclusion criteria

  • Primary headache,
  • headache on the day of investigation,
  • Hypertension,
  • hypotension,
  • pregnant/nursing
  • Daily intake of medication (except oral contraceptives)
  • Cardiovascular or CNS disease
  • Drug/Alcohol abuse
  • Psychiatric disease

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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