PGTai Results for Embryos Cultured in Sequential Versus Single Step Media

G

Ganin Fertility Center

Status

Unknown

Conditions

Mosaicism
Aneuploidy Rate
Infertility

Treatments

Other: Sequential media
Other: Single step media

Study type

Interventional

Funder types

Other

Identifiers

NCT04485910
MH0004

Details and patient eligibility

About

A prospective cohort study undergoing ICSI at a private fertility center in Egypt

Full description

Purpose: To evaluate PGTai results for embryos cultured in sequential versus single step media. Method: Injected oocytes will divided between Continuous Single Culture-NX media (CSC- NX) with 10% SSS the first group (Irvine, USA) and the other group will be cultured in sequential cleavage and blastocyst media with 10% SPS (SAGE, Denmark). All blastocytes with 4BB quality and better according to Gardner's criteria 1999 will go through PGTA procedures with PGTai confirmation.

Enrollment

200 estimated patients

Sex

All

Ages

18 to 37 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Female age ≤37 years with ≥ 8 mature oocytes
  • Male partner had normal semen parameters according to WHO 2010
  • PGT-A was done at the blastocyst stage

Exclusion criteria

  • sperm or oocyte donor
  • severe male factors according to WHO 2010

Trial design

200 participants in 2 patient groups

Single step media
Active Comparator group
Description:
Embryos cultured in single step media
Treatment:
Other: Single step media
Sequential media
Active Comparator group
Description:
Embryos cultured in sequential media
Treatment:
Other: Sequential media

Trial contacts and locations

0

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Central trial contact

Amr Elshimy, BSc.; Manar M Hozyen, MSc.

Data sourced from clinicaltrials.gov

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