Phaco-Trabeculotomy Vs Phaco-Trabeculectomy (PDT vs PT)

Assiut University

Status: Completed

Conditions: Ophthalmopathy; Glaucoma; Glaucoma, Angle-Closure

Treatments: Procedure: Phacoemulsification combined with trabeculectomy; Procedure: Phacoemulsificaiton combined with ab-externo trabeculotomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04683055

IRB17300506

Details and patient eligibility

About

A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.

Full description

Patients were randomized into two groups: group A : patients will undergo two site phacoemulfication combined with trabeculectomy Group B with Phacoemulsification combined with ab-externo trabeculotomy. Preoperative assessments including full ophthalmic examination, anterior segment Optical Coherence Tomography (OCT) of the angle , endothelial cell count , visual fiend Perimetry and Biometry. Patients were followed up: first day, first week and every two months for 6 month. We will compare adverse effects and outcomes in both groups.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with chronic angle closure glaucoma, with or without peripheral anterior synechiae, age more than 18

Exclusion criteria

• Patient unable for follow up
• Patients with corneal or retinal disease that affects visual outcome of surgery
• Patients with previous glaucoma procedure in the eye of study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Phacoemulsification combined with trabeculectomy

Active Comparator group

Description:

Patients will undergo Two site phacoemulsification combined with trabeculectomy with Mitomycin C

Treatment:

Procedure: Phacoemulsification combined with trabeculectomy

Phacoemulsificaiton combined with ab-externo trabeculotomy

Active Comparator group

Description:

Patients will undergo two phacoemulsification combined with deep sclerectomy and ab-externo trabeculotomy

Treatment:

Procedure: Phacoemulsificaiton combined with ab-externo trabeculotomy