Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention

Wake Forest University (WFU)

Status: Completed

Conditions: Coronary Artery Disease; Hyperlipidemia

Treatments: Other: Pharmacist Intervention in lipid therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06647238

IRB00118029

Details and patient eligibility

About

The primary objective of this research project is to compare the effect of pharmacist interventions versus usual care in the implementation of guideline directed lipid lowering therapies for secondary prevention.

Full description

Studies have shown prevention of cardiovascular adverse events is directly proportional to percent reduction in low-density lipoprotein (LDL). This evidence explains why LDL targets for secondary prevention have continued to be lowered. Cholesterol guidelines have been updated recently and encourage the use of multiple lipid lowering therapies, in addition to statins, for secondary prevention. However, these novel agents can be expensive and difficult to acquire, making prescribing challenging for providers.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of coronary artery disease
• low-density lipoprotein (LDL) > 55
• Primary Care Physician at 1 of 6 identified clinics

Exclusion criteria

• Patients who are no longer an active patient of one of the internal medicine practices
• Patients whose cholesterol is managed by another practice
• Women of childbearing age/potential
• Patients residing in hospice/Long Term Care facilities
• End-stage liver disease

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

Pharmacist Intervention

Experimental group

Description:

Pharmacist review of patient chart and follow up visits to prescribe appropriate therapy for hyperlipidemia.

Treatment:

Other: Pharmacist Intervention in lipid therapy

Control

No Intervention group

Description:

Chart review only