Status
Conditions
Treatments
About
This project will develop and assess the feasibility and acceptability of a salive-based assay to monitor adherence to Mass Drug Administration (MDA) campaigns within Soil-transmitted helminthiasis (STH) control programs, evaluating the salive and serum pharmacokinetics of ALBENDAZOLE (ABZ) and its metabolites.The final goal is to obtain a field ready tool for the measurement of adherence to anthelmintic treatment at a community level that serves as a coverage/adherence indicator and a reference standard for other monitoring tools.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
Body Mass Index: 18 to 25.
Physical exam without significant abnormal findings.
Exclusion criteria
Pregnancy
Lactation
Use of ABZ or other benzimidazole drugs in the previous 30 days
History of intolerance to ABZ
Malabsorption and/or other gastrointestinal conditions that might compromise ABZ absorption.
Primary purpose
Allocation
Interventional model
Masking
12 participants in 1 patient group
Loading...
Central trial contact
Alejandro J Krolewiecki, MD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal