Pharmacokinetics of Carnosine

Tufts University

Status: Completed

Conditions: Oxidative Stress

Treatments: Other: Chicken broth; Other: Chicken; Other: Beef; Dietary Supplement: pure carnosine

Study type: Interventional

Funder types: Other

Identifiers

NCT00721708

TMC/TUHS IRB 7737

Details and patient eligibility

About

The absorption kinetics of dietary carnosine (β-alanyl-L-histidine) will be determined in the healthy adults.

Enrollment: 4 patients

Sex: Female

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adult
• normal hematological parameters, normal serum albumin, normal liver function, normal kidney function

Exclusion criteria

• History of smoking or alcoholism

Trial design

4 participants in 4 patient groups

1

Experimental group

Description:

Carnosine(450 mg)

Treatment:

Dietary Supplement: pure carnosine

2

Experimental group

Description:

Beef (150g)

Treatment:

Other: Beef

3

Experimental group

Description:

chicken (150g)

Treatment:

Other: Chicken

4

Experimental group

Description:

Chicken broth (obtained from 150 g of chicken breast)

Treatment:

Other: Chicken broth