Status
Conditions
Treatments
About
Ex vivo lung perfusion (EVLP) is an established strategy to evaluate and optimize high-risk donor lungs that would otherwise be rejected for transplantation mainly due to the presence of edema or infection. Extracorporeal circuits may negatively affects pharmacokinetic (PK) of several drugs including antibiotics, thus exposing patients to risk of therapeutic failure or drug toxicity. The investigators set out to examine the concentration of imipenem in lung perfusate and in lung biopsy during EVLP, and its clinical impact.
Enrollment
Sex
Volunteers
Inclusion criteria
Exclusion criteria
30 participants in 1 patient group
Loading...
Central trial contact
Vito Fanelli, MD, PhD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal