Pharmakokinetik of Caffeine in Epiretinal Membranes After Oral Intake: a Pilot Study

Vienna Institute for Research in Ocular Surgery

Status: Completed

Conditions: Epiretinal Membrane

Treatments: Procedure: vitrectomy with membrane peeling

Study type: Interventional

Funder types: Other

Identifiers

NCT03646682

CaffERM

Details and patient eligibility

About

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry.

Full description

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry. One hour before surgery patients in the caffeine Group will receive 180mg of caffeine. in all patients vitrectomy with Membrane Peeling will be performed, due to epiretinal membranes

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• epiretinale membrane

Exclusion criteria

• none

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

caffeine group

Experimental group

Description:

180mg of caffeine will be given orally one jour before vitrectomy with membrane peeling

Treatment:

Procedure: vitrectomy with membrane peeling

control group

Active Comparator group

Description:

no caffeine will be given before vitrectomy with membrane peeling, patients are drinking no coffee in general

Treatment:

Procedure: vitrectomy with membrane peeling