Phase I Trial From GRID 18F-FDG-PET Biological Imaging-guided Intensitymodulated Radiotherapy (BG-IMRT) With Patients With Recurrent or New Head or Neck Tumor in Previously Radiated Area

Ghent University Hospital (UZ)

Status and phase: Terminated; Phase 1

Conditions: Head and Neck Tumors

Treatments: Radiation: GRID radiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00528294

2007/010

Details and patient eligibility

About

This trials examines the feasibility of GRID-therapy combined with biologically imaging based IMRT (BG-IMRT). Within this trial, the strict toxicity parameters of primary treatment of head and neck tumors are used. The GRID and BG-IMRT technique might be possible to reduce the total radiation dose 2 to 3 times.

Enrollment: 12 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Recurrent or new head or neck tumor
• 18 years or older

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

1

Experimental group

Description:

GRID-radiotherapy followed by biological imaging guided IMRT

Treatment:

Radiation: GRID radiotherapy