Phase II Study of SBRT as Treatment for Oligometastases in Prostate Cancer

Grupo de Investigación Clínica en Oncología Radioterapia

Status

Completed

Conditions

Oligometastatic Prostate Cancer

Treatments

Radiation: Stereotactic Body Radiation Therapy for Oligometastases

Study type

Interventional

Funder types

Other

Identifiers

NCT02192788

SBRT-SG 05

Details and patient eligibility

About

This study aims to probe the effect of SBRT as a treatment oligometastases of prostate cancer, regardless of basal treatment received, and I know the response, biochemical control, the progression-free survival as well as their impact on quality of life.

Primary Objective: Local and symptomatic oligometastases Control of prostate cancer treated by SBRT.

Secondary Objectives: Analyzing biochemical progression rates, progression-free survival, chemotherapy-free survival and overall survival. Analyze toxicities and quality of life of patients before and after treatment

Enrollment

68 patients

Sex

Male

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with histologically confirmed prostate cancer, who are currently being oligometastases / oligorrecurrencia after primary treatment for their disease.
Aged ≥ 18 years
Time to biochemical recurrence more than 1 year
PSA doubling time> 3 months
Less than 5 bone metastases location (including spinal) or lymph node.
Without other metastases or recurrences by Choline PET or / and NMR Diffusion Length.
Signed and dated written informed consent form.

Exclusion criteria

Patients currently treatment with abiraterone, enzalutamide, chemotherapy, immunotherapy or radioisotopes.
Patients unwilling or unable to comply with protocol requirements and scheduled visits.