Phenotyping Adherence Through Technology-Enabled Reports and Navigation

Northwestern University

Status: Completed

Conditions: Medication Adherence

Treatments: Behavioral: The PATTERN Intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05766423

P30AG059988 (U.S. NIH Grant/Contract)

STU00217555

Details and patient eligibility

About

This study is being conducted to adapt and pilot test a technology-enabled, primary care strategy for routinely monitoring medication use and adherence among older adults with multiple chronic conditions and polypharmacy.

Full description

Our study aims are to:

Aim 1: Adapt the PATTERN intervention for use in primary care using input from key stakeholders. During Aim 1, the Northwestern research team will solicit opinions from key informants (patients, clinicians, practice administrators) to ensure PATTERN meets the needs of primary care.

Aim 2: Assess the PATTERN intervention's feasibility and acceptability for use in primary care. During Aim 2, the investigators will conduct a 2-arm, patient-randomized controlled trial at a Northwestern Medicine primary care practice. Participants will be recruited and randomly assigned, using a random number generator application, to either the PATTERN intervention or usual care. Usual care refers to the normal standard clinical practices at the participating practice. Participants will be followed for 6 months.

Enrollment: 73 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Each participant must:

• Be an adult aged 65 or older
• Speak English as their primary language
• Have multiple chronic conditions
• Be prescribed 8 or more medications
• Be primarily responsible for administering own medication
• Receive medical care at the participating primary care practice
• Have access to the internet and an active email address
• Be signed up for the patient portal (MyChart)

Exclusion criteria

No participant can:

• Have severe, uncorrectable visual, hearing or cognitive impairments that would preclude study consent or participation

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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73 participants in 2 patient groups

Usual Care

No Intervention group

Description:

Usual care includes: 1. The normal standard clinical practices at the participating practice. 2. No specific materials to promote PATTERN, and no additional materials that include adherence assessments or care alert notifications.

The PATTERN Intervention

Active Comparator group

Description:

The intervention components include: 1. An adherence assessment completed by participants ahead of a regularly scheduled clinic visit. 2. Care alert notifications directed to a nurse pool and/or member of the clinical care team.

Treatment:

Behavioral: The PATTERN Intervention