Phloroglucinol Effectiveness on Shortening the Duration of Active Phase of Labor

Muhammad Aamir Latif

Status: Completed

Conditions: Labor

Treatments: Drug: Phloroglucinol

Study type: Interventional

Funder types: Other

Identifiers

NCT07184099

Dr-Tahira-Attock

Details and patient eligibility

About

This study was planned to fill the gaps regarding the effectiveness of phloroglucinol on the duration of active phase of labor.

Full description

In today's era, the focus has shifted from a "wait and watch" policy to "active intervention sooner than later" to enhance better labor outcomes. Using an ideal antispasmodic drug would help achieve a rapid and prolonged effect on cervical dilation, with no adverse impact on uterine contractions or causing uterine inertia. If the current study finds phloroglucinol effective in shortening the duration of the active phase of labor, it would help achieve better patient outcomes.

Enrollment: 134 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women aged between 18-35 years
• Period of gestation above 37 weeks.

Exclusion criteria

• Women with cephalopelvic disproportion
• Double scare uterus
• Fetal distress
• Life threatening bleeding
• Eclampsia
• History of heart disease
• Known allergy to phloroglucinol

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

134 participants in 2 patient groups

Phloroglucinol group

Experimental group

Description:

Phloroglucinol was administered as intravenous stat infusion with Ringer Lactate infusion.

Treatment:

Drug: Phloroglucinol

Placebo group

No Intervention group

Description:

The patients were given only Ringer Lactate infusion.