Phospholipid Absorption of a Milk Phospholipid

University of Jena

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Milk phospholipid

Study type: Interventional

Funder types: Other

Identifiers

NCT01327430

LSEP H44-10

Details and patient eligibility

About

The aim of the study is to investigate parameters of the lipid metabolism in plasma and feces of healthy subjects after a dietary supplementation of different dosages of milk phospholipids.

Full description

To date the mechanisms for the intestinal absorption of glycerophosphates and sphingolipids are not completely investigated. It is assumed, that sphingolipids and sterols compete for intestinal absorption. In addition it is unclear, if a dietary phospholipid supplementation may influence the phospholipid concentration in plasma.

To evaluate the effect of a dietary phospholipid supplementation 15 healthy female subjects received over 10 days daily 3 g of milk phospholipids stirred in a dairy product. During the following 10 days the subjects were supplemented with daily 6 g milk phospholipid. Finally, the subjects received over 10 days 6 g of the milk phospholipid in a dairy product and 2 g of plant sterols serving a commercial product.

Enrollment: 15 patients

Sex: Female

Ages: 30 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female
• age: between 30 and 45 years

Exclusion criteria

• metabolic diseases
• arteriosclerosis
• pregnancy and breast feeding

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Phospholipid supplementation

Experimental group

Description:

Supplementation of milk phospholipid

Treatment:

Dietary Supplement: Milk phospholipid