Phosphorus Education and Adherence in Hemodialysis Patients

Jen-Ai Hospital Institutional Review Board

Status: Invitation-only

Conditions: Hemodialysis; Nursing Education

Treatments: Behavioral: Nursing education AB+3; Behavioral: Nursing education B+3; Behavioral: Nursing education A+2; Behavioral: Nursing education B+2; Behavioral: Nursing education A+3; Behavioral: Nursing education AB+2; Behavioral: Nursing education AB+1; Behavioral: Nursing education B+1; Behavioral: Nursing education A+1

Study type: Interventional

Funder types: Industry

Identifiers

NCT07080840

WHChen

Details and patient eligibility

About

By applying statistical methods such as analysis of variance (ANOVA), this study incorporates both the content and the intensity (frequency) of educational interventions to design multiple regression models for evaluating education strategies. Through each round of laboratory data, the investigators aim to identify the most effective educational model using empirical data. The findings will not only improve phosphorus management and enhance the quality of care but also reduce unnecessary nursing workload and help establish an optimal educational protocol and training framework.

Based on literature review and clinical experience, it is well recognized that, in addition to receiving regular and adequate dialysis, effective phosphorus control relies heavily on patients' daily dietary selection and the appropriate use and frequency of phosphate binders. Hence, this study aims to investigate the correlation between phosphorus control and patient education delivered by nursing staff, focusing on dietary management, phosphate binder usage, and knowledge of dialysis principles.

By applying statistical methods such as analysis of variance (ANOVA), this study incorporates both the content and the intensity (frequency) of educational interventions to design multiple regression models for evaluating education strategies. Through each round of laboratory data, we aim to identify the most effective educational model using empirical data. The findings will not only improve phosphorus management and enhance the quality of care but also reduce unnecessary nursing workload and help establish an optimal educational protocol and training framework.

Enrollment: 45 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who have been on dialysis for more than one year, have intact self-awareness, and are currently taking phosphate-binding medications.

Exclusion criteria

• Patients who have been on dialysis for less than one year, lack self-awareness, or are not taking phosphate-lowering medications.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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45 participants in 9 patient groups

Nursing Education A+1

Experimental group

Description:

Arm: A + 1 Patients received dietary education once. The session focused on phosphorus-rich food identification, dietary restrictions, and basic meal planning.

Treatment:

Behavioral: Nursing education A+1

Nursing Education A+2

Experimental group

Description:

Arm: A + 2 Patients received dietary education twice. The program reinforced dietary knowledge through interactive review and provided individual nutrition tips.

Treatment:

Behavioral: Nursing education A+2

Nursing Education A+3

Experimental group

Description:

Arm: A + 3 Patients received dietary education three times. Sessions included detailed meal planning, food label reading, and repetition to promote long-term adherence.

Treatment:

Behavioral: Nursing education A+3

Nursing Education B+1

Experimental group

Description:

Arm: B + 1 Patients received medication education once. The session introduced phosphate binders, usage timing, and basic instructions for improving adherence.

Treatment:

Behavioral: Nursing education B+1

Nursing Education B+2

Experimental group

Description:

Arm: B + 2 Patients received medication education twice. The intervention emphasized adherence barriers and strategies for taking binders correctly with meals.

Treatment:

Behavioral: Nursing education B+2

Nursing Education B+3

Experimental group

Description:

Arm: B + 3 Patients received medication education three times. The sessions included repeated instruction, practical timing scenarios, and Q\&A with nursing staff.

Treatment:

Behavioral: Nursing education B+3

Nursing Education AB+1

Experimental group

Description:

Arm: A+B + 1 Patients received combined dietary and medication education once. The session addressed both phosphorus intake from food and proper medication use.

Treatment:

Behavioral: Nursing education AB+1

Nursing Education AB+2

Experimental group

Description:

Arm: A+B + 2 Patients received combined dietary and medication education twice. The intervention highlighted food-drug interactions and provided dual-domain strategies.

Treatment:

Behavioral: Nursing education AB+2

Nursing Education AB+3

Experimental group

Description:

Arm: A+B + 3 Patients received combined dietary and medication education three times. The sessions offered integrated guidance, practice tools, and individualized plans.

Treatment:

Behavioral: Nursing education AB+3