Photobiomodulation Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease

Lowell General Hospital

Status and phase: Completed; Phase 2

Conditions: COVID-19

Treatments: Other: Regular Inpatient Medical Care; Device: MLS Laser

Study type: Interventional

Funder types: Other

Identifiers

NCT04391712

2020.01

Details and patient eligibility

About

The aim of this study is to evaluate the effectiveness of MLS laser therapy as a treatment for pulmonary complications due to COVID-19 infection.

Full description

Participants will be randomized into treatment vs. control group. Both groups will receive regular inpatient medical treatment. Participants in the experimental arm will receive laser treatments once daily for 4 days. Treatments will be delivered to the patients in a prone position using a 10 by 25 cm laser field across each lung with 7j/cm2 at 1500 Hz. Standard nursing protocols would be used to identify participant's pulmonary status throughout treatment.

Enrollment: 10 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COVID-19 positive
• Pulmonary compromise requiring oxygen support of approximately 2-6 liters
• Able to self prone, or support in self-sitting position

Exclusion criteria

• Ventilator management
• Patients with autoimmune disorders or inflammatory conditions not related to COVID-19
• Pregnant women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Experimental

Experimental group

Description:

Participants will receive MLS laser treatment along with regular inpatient medical care.

Treatment:

Device: MLS Laser

Control Group

Active Comparator group

Description:

Participants will receive regular inpatient medical care.

Treatment:

Other: Regular Inpatient Medical Care