Photon/Proton Radiation Therapy for Oropharyngeal Cancers (OP01)

University of Florida

Status: Terminated

Conditions: Oropharyngeal Cancers

Study type: Observational

Funder types: Other

Identifiers

NCT00797446

UFPTI 0601-OP01

Details and patient eligibility

About

The purpose of this study is to collect information from the questionnaire and medical records to see what effects proton radiation has on cancer and collect and analyze morbidity outcomes: incidence of xerostomia (dry mouth) and tumor control.

Full description

This is an outcomes study and is designed to collect information from the questionnaire and medical records to see what effects proton radiation has on cancer and collect and analyze morbidity outcomes: incidence of xerostomia (dry mouth) and tumor control.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Biopsy-proven squamous cell carcinoma of oropharynx (tonsillar pillars, tonsillar fossa, soft palate, base of tongue).

• Stage-grouping:

  • Stage I (T1N0)
  • Stage II (T2N0)
  • Favorable Stage III (T1N1/T2N1) and selected stage IV (T1-T2 early N2b)2 or less lymph node and 2 or less cm diameter lymph node
  • Unfavorable stage III and selected stage IV (any T, N2c/N3)

• Surgery of the primary tumor/lymph nodes is limited to incisional/excisional biopsies.

• Will receive treatment with proton radiation.

Exclusion criteria

• Evidence of distant metastasis.
• Previous irradiation for head and neck cancer.

Trial design

10 participants in 1 patient group

Photon/Proton Radiation Therapy

Description:

Data collection will be obtained from the patient's medical records including initial evaluation, pathology report, dosimetry information, radiotherapy completion records and follow-up.