Photoplethysmography for Diagnose Incipient Hypovolemia

Hospital Privado de Comunidad de Mar del Plata

Status: Completed

Conditions: Hypovolemia

Treatments: Diagnostic Test: Finger photoplethysmography

Study type: Observational

Funder types: Other

Identifiers

NCT05512611

2919-2809/2022

Details and patient eligibility

About

Hypovolemia caused by acute bleeding increased morbi-mortality in emergency and operatin rooms. Precise real-time diagnosis of incipient acute hypovolemia is lacking at the bedside. We hypothesize that the infrared-red signals of pulse oximetry are sensitive to acute changes in patient's volemia. We aimed to test this hypothesis in a cohort of healthy blood donors as a model of simulated acute hypovolemia.

Full description

This is a prospective and observational study designed to determine if the changes observed in finger photoplethysmographic waveform can detect incipient hypovolemia. The investigators will studied 60 blood donor volunteers as a model of slight hypovolemia (8-10% of the volemia). Vital signs and photoplethysmography will be recorded in the thumb of the tested hand during a standard blood donation protocol. Recorded data will be analyzed and compared before and after blood donation .

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Written Inform Consent
• weight > 50 kg,
• hemoglobin >12.5 gr/dl

Exclusion criteria

• pregnancy,
• ≤ 12 months from delivery or abortion,
• symptoms of allergy,
• fever >37 °C,
• infectious diseases,
• addictions,
• volunteers that received previous blood transfusions