Phototherapeutic Keratectomy (PTK) With Mitomycin in Adenoviral Opacities

Federal University of São Paulo

Status: Unknown

Conditions: Corneal Opacity; Keratitis

Treatments: Procedure: PTK with mitomycin in Adenoviral Opacities

Study type: Interventional

Funder types: Other

Identifiers

NCT00492245

CEP0075/06

Details and patient eligibility

About

The present study was designed to evaluate the treatment of adenoviral corneal opacities with PTK and mitomycin C.

Full description

Epidemic keratoconjunctivitis is a very common disease, some patients developed a complication after the infection wich is corneal infiltration. Topical treatment sometimes helps to avoid loss of visual acuity. Therefore recurrence of the opacities after topical drops is observed. When corneal fibrosis occur is difficult to achieve visual rehabilitation with topical approach. This study evaluate pre and postoperative data of patients with subepithelial fibrosis caused by adenoviral infiltrates submitted to phototherapeutic keratectomy (PTK) using mitomycin C.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• visual acuity worse than 20/40, caused by central subepithelial fibrosis

Exclusion criteria

• pregnancy, age less than 18 years-old or more than 80 years-old.
• diabetes, autoimmune diseases, corneal thickness less tha 400 micron.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)