Physical Activity and Cardiorespiratory Fitness in Adolescents With Autism Spectrum Disorder (PAASD)

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Autism Spectrum Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT04950517

S65474

Details and patient eligibility

About

The purpose of this study is to increase knowledge and insights with regard to physical activity behavior in adolescents with Autism Spectrum Disorder.

Full description

Low levels of physical activity (PA) in adolescents with Autism Spectrum Disorder (ASD) increase the risk for both physical and mental health problems during adolescence and subsequent adulthood. To enable the identification of adolescents with ASD at risk for developing an inactive lifestyle and to inform the future design of high-quality, evidence-based and ASD-specific PA interventions and programs, several gaps of the current literature need to be addressed.

1. To date, no PA and cardiorespiratory fitness (CRF) tests have been validated in adolescents with ASD, causing an inability to accurately assess and interpret these two important health markers.
2. There is a lack of knowledge regarding PA correlates in this population, resulting in difficulties to identify adolescents with ASD at risk of developing an inactive lifestyle.
3. It is still unknown why adolescents with ASD are predominantly inactive and qualitative research of the perspectives of adolescents with ASD towards PA participation in order to understand their PA behavior is scant.

Therefore, the aims of this project with regard to adolescents with ASD are:

1. To examine the concurrent validity of two self-report PA instruments and the concurrent validity and test-retest reliability of a submaximal CRF test.
2. To determine potential complex and multiple (interactions between) correlates of PA, using a comprehensive assessment protocol.
3. To explore the perspectives of adolescents with ASD concerning the barriers and facilitators of PA participation.

Enrollment: 76 patients

Sex: All

Ages: 12 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent/assent
• ASD diagnosis according to the DSM-IV/5
• Proficient knowledge of Dutch

Exclusion criteria

• A physical disability hampering the administration of the standardized tests (e.g. unable to sit on a bicycle/perform a motor skill test in standing position)
• Participants with an intellectual disability (defined as an intelligence quotient < 70)
• Participants with severe medical problems (e.g. severe metabolic disorders, oncological disease, diabetes), because of safety reasons
• Wave 1 participants only: the use of antipsychotics, because of safety reasons in the context of performing a maximal exercise test
• Participation in another clinical trial
• In case of pregnancy

Trial design

76 participants in 2 patient groups

Wave 1 participants

Description:

The study consists of three work packages. Wave 1 participants will be included in all work packages.

Wave 2 participants

Description:

The study consists of three work packages. Wave 2 participants will only be recruited for work package 2.