Physical Activity and Food Intake Interaction: Effect of Weight Loss in Obese Adolescent

University Hospital, Clermont-Ferrand

Status: Completed

Conditions: Obesity

Treatments: Behavioral: Physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT02664844

CHU-0255

Details and patient eligibility

About

In obese adolescents, energy expenditure (EE) of chronic high intensity muscular exercise (> 70% VO2max) conducted one hour before a meal causes an anorectic effect at lunch and dinner the same day. The effect on food intake of the distribution of this exercise into two sessions during 24h remains to be determined. In addition, a multidisciplinary load of obesity generates a loss of body weight in the short term, which we do not know the effects on energy balance. To our knowledge, the impact of weight loss on the anorectic effect of muscle exercise is unknown.

Full description

Two measuring sequences will be carried out before (M0) and after 4 months (M4) of a multidisciplinary treatment program of four months. Each sequence will have three days: a "sedentary" day (SED) and two days "exercise" (EX). During the exercise day "EX1", a continuous intense exercise will be conducted for 40 min at 70% VO2max of subjects. During the second day exercise "EX2" teenage realize two exercise representing the same DE as EX1 in the morning (50% ED) and late afternoon (50% ED). The multidisciplinary management program (without energy restriction) controlled by institution consists of nutrition education, physical activity and therapeutic education. The exercise program will involve the activity sessions controlled and supervised by a sports educator and interactive sessions using a scientifically validated physical activity program (Biomouv®).

Enrollment: 20 patients

Sex: Female

Ages: 12 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Overweight adolescents (over the 90 th percentile of the international cut-off point)
• Sedentary (according to the IPAQ-A questionnaire)
• Without eating disorders (according to the DEBQ questionnaire)

Exclusion criteria

• Medical or surgical antecedents that are incompatible with the study: cardiovascular, endocrine or digestive disease.
• Drugs that could interfere with the results of the study
• Surgical intervention in the 3 months
• Regular consumption of tobacco or Alcohol
• patients on a diet with caloric restriction
• Refusal to sign the consent form
• Regular practice of sport and intensive

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Obese adolescent

Experimental group

Treatment:

Behavioral: Physical activity