Physical Activity and Health of Children With Cancer in Remission

Hadassah Medical Center

Status: Completed

Conditions: Children; Cancer; Exercise

Treatments: Behavioral: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT00839904

GDR2-HMO-CTIL

Details and patient eligibility

About

Physical activity is a well-known and powerful tool in medicine,having preventive, palliative, and curative properties. This has not been sufficiently examined in children in remission from cancer. In this study, children in remission from cancer will be divided into exercise and control groups. The interventional group will perform two supervised, 60-minute weekly exercise sessions. Outcome measures of the exercise intervention will be quality of life, mood, cardiorespiratory fitness, body composition and bone mineral density.

Enrollment: 22 patients

Sex: All

Ages: 6 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children aged 6-16
• remission from cancer
• >6 months after completion of all therapy

Exclusion criteria

• informed consent not given in writing
• refusal of tests: blood, fitness, questionnaires or DEXA
• locomotive handicaps
• extreme fatigue, nausea, dyspnea
• concurrent acute illness
• recent (less than 3 months) hospitalization
• documented (echocardiographic or nuclear medicine) decrease in cardiac function
• abnormal blood tests: Hb < 10 gr/dl, neutropenia < 500/mm3, thrombocytopenia < 50,000/mm3
• additional chronic health conditions unrelated to cancer (e.g. celiac disease, cerebral palsy, Down's syndrome)

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

22 participants in 2 patient groups

exercise

Experimental group

Description:

two supervised, 60-minute weekly exercise sessions + instructions to perform additional physical activities throughout the day

Treatment:

Behavioral: exercise

control

No Intervention group

Description:

no intervention