Physical Activity and Quality of Life in Postmenopausal Women

Wissal Abassi

Status: Completed

Conditions: Fitness Testing; Quality of Life

Treatments: Behavioral: Combined Aerobic and Muscle-Strengthening Training Program

Study type: Interventional

Funder types: Other

Identifiers

NCT07074132

PA-MenQL25

Details and patient eligibility

About

The goal of this clinical trial is to investigate the effects of a combined aerobic and muscle-strengthening training program on body composition, physical fitness, and quality of life in overweight or obese postmenopausal women. The main question it aims to answer is: Does this training modality improve body composition, enhance physical fitness, and increase quality of life in this population ? Researchers will compare outcomes between an experimental group following the training protocol and a control group with no training intervention, in order to determine whether the program leads to measurable improvements in these parameters. Participants in the training group will engage in aerobic exercise at 50-70% of heart rate reserve (HRR) and strength training at 60-70% of one-repetition maximum (1-RM), three times per week for 8 months.

Participants in the control group will not engage in any structured physical training and will be asked to maintain their usual daily routines.

Full description

Overweight and obesity in postmenopausal women are associated with adverse changes in body composition, decreased physical fitness, and a decline in overall quality of life. The postmenopausal period is marked by hormonal changes that contribute to increased fat accumulation, loss of muscle mass, and heightened vulnerability to metabolic and cardiovascular diseases. These changes often lead to reduced functional capacity and well-being. Although exercise has been widely recognized as an effective strategy for improving health outcomes, there is a lack of long-term intervention studies combining aerobic and strength training in this specific population. The purpose of this clinical trial is to investigate the effects of a combined aerobic and muscle-strengthening training program for 8 months on body composition, physical fitness, and quality of life in overweight or obese postmenopausal women.

Thirty-six overweight/obese postmenopausal women were randomly assigned to either a training (n = 18), or a control group (n = 18). The training group will engage in aerobic exercise at 50-70% HRR and strength training at 60-70% 1-RM, three times per week for eight months. The control group will not participate in any structured physical training and will be instructed to maintain their usual lifestyle habits. Assessments of body composition, physical fitness, and quality of life were assessed before and after the intervention.

Enrollment: 36 patients

Sex: Female

Ages: 50 to 62 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age range (50-62 years).
• Postmenopausal women (absence of menstruation > 12 months).
• Body mass index (BMI) ≥ 25 kg/m².
• Body weight remained constant (±2 kg) for the past 3 months.
• Stable dietary habits and physical activity for at least 3 months.
• Sedentary lifestyle (physical activity less than 1 hour per week).

Exclusion criteria

• Medical contraindications to physical activity.
• Metabolic, hormonal, orthopedic, or cardiovascular diseases.
• Current use of hormone replacement therapy or any prescribed medication.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

36 participants in 2 patient groups

Training group

Experimental group

Description:

The experimental group performed a combined training program consisting of aerobic training at 50-70% of heart rate reserve (HRR) and muscle-strengthening training at 60-70% of one-repetition maximum (1-RM), three times per week for eight months.

Treatment:

Behavioral: Combined Aerobic and Muscle-Strengthening Training Program

Control group

No Intervention group

Description:

No training intervention was intended for the control group.