Physical Activity for Reduction of Recurrence Rate After Adjuvant Chemotherapy for Localised Colorectal Carcinoma

Austrian Breast & Colorectal Cancer Study Group

Status: Completed

Conditions: Colorectal Carcinoma

Treatments: Other: Physical exercise

Study type: Observational

Funder types: NETWORK

Identifiers

NCT01210313

EXERCISE (Other Identifier)

ABCSG C07

Details and patient eligibility

About

• feasibility of physical activity
• increase of physical conversation
• Quality of Life (optional)
• vascular and metabolic effects

Full description

In this phase II pilot project the feasibility of a defined medical physical activity should be verified for increased physical conversation. The study is conducted multicentric (single group) with a study population of 30 patients. After completion of adjuvant chemotherapy the patients will participate a defined physical training, 3 times per week within a time period of 52 weeks. Planned study duration 2 years.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• complete resected, histologically confirmed adeno carcinoma of colon or rectal and condition after (neo-)adjuvant therapy either in (1) stage III or (2) stage II with risk factor
• 4-16 weeks after the end of an adjuvant chemotherapy
• ECOG 0,1
• Age > 18 years
• adequate liver-, nephro- and hemogram parameters
• physical eligibility

Exclusion criteria

• significant comorbidities which exclude the participation
• evidence of local recurrence or distant metastases
• non-compliance of subject
• other malignancy within the last 5 years (except: skin basalioma, cervix carcinoma in situ)
• clinically significant cardiovascular diseases
• treatment with beta blocker without possibility of adjustment
• left bundle-branch block
• simultaneous chemotherapy or radiotherapy
• pregnancy

Trial design

30 participants in 1 patient group

Physical exercise

Description:

No treatment, only physical examinations accompanying physical exercise

Treatment:

Other: Physical exercise