Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes

University of Pittsburgh

Status: Completed

Conditions: Physical Activity; Abdominal Obesity

Treatments: Other: Control; Other: Resistance Exercise; Other: Aerobic exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01323088

1R21DK083654-01A1

Details and patient eligibility

About

In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, ectopic fat in the liver and skeletal muscle, and risk of type 2 diabetes in overweight girls.

Enrollment: 44 patients

Sex: Female

Ages: 12 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy overweight (BMI >-95th) youth between 12 and 18 years of age
• Waist circumference >-75th percentile
• Sedentary (no structured exercise >2 times/week for past 6 months)
• Non-smokers, non-diabetic, no medical conditions
• Weight stable for past 3 months

Exclusion criteria

• Smokers
• Diabetes
• Psychiatric disorders
• Syndromic obesity
• Pregnancy
• Taking medications known to affect study outcomes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 3 patient groups

Control

Other group

Description:

Standard care control (no-exercise)

Treatment:

Other: Control

Aerobic Exercise

Active Comparator group

Treatment:

Other: Aerobic exercise

Resistance Exercise

Active Comparator group

Treatment:

Other: Resistance Exercise