Physical Activity Program and Energy Intake Control in Obese Adolescents

Université Blaise Pascal, Clermont-Ferrand

Status: Unknown

Conditions: Pediatric Obesity

Treatments: Behavioral: Physical activity intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT02482220

AU 1178

Details and patient eligibility

About

Acute exercise of high intensity has been shown to induced nutritional adaptations in obese adolescents. Indeed, several studies have shown that about 30 minutes of intensive exercise (above 70% of the adolescents maximal aerobic capacities) can favor reduced-energy consumption at the following meal with no modification of their appetite feelings. Although it is suggested that chronic physical activity programs can induce energy intake modifications, this has never been clearly studied. The aim of this work is to compare different physical activity programs (low vs. high intensity programs) in terms of energy intake, appetite feelings and appetite-regulating hormones, in obese adolescents.

Full description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

• anthropometric measurements
• Body composition assessed by DXA
• Maximal aerobic test
• Blood samples (appetite-regulating hormones)
• daily energy intake assessment during a 24h intake exploration.

The adolescents recruited will then be randomly assigned to one of the two intervention groups:

• High Intensity program or moderate intensity program. Those two physical activity programs will last 4-months and will be composed of 3 to 4 exercise sessions per week. The High intensity program will consists in High intensity interval exercises starting at 70% of the adolescents' capacities at the beginning to end around 95%. The moderate intensity program will propose continuous exercises set between 50-65% VO2max.

No energy intake intervention will be performed.

By the end of the 4-months intervention, all the clinical examinations performed before the intervention will be repeated.

Enrollment: 70 estimated patients

Sex: All

Ages: 12 to 15 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 12 to 15 years old adolescents
• Obese according to international values for BMI
• Being registered to the national social security insurance
• no eating disorders
• no medications
• metabolic disorders

Exclusion criteria

• metabolic disorders
• food disorders
• physical disability

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

High intensity

Experimental group

Description:

in this group, the participants will follow a high intensity physical activity program (High Intensity Interval exercise from 75 to 95% VO2max)

Treatment:

Behavioral: Physical activity intervention

Moderate intensity

Experimental group

Description:

in this group, the participants will follow a moderate intensity physical activity program (Intensity from 50 to 65% VO2max)

Treatment:

Behavioral: Physical activity intervention