Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation

National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland

Status: Completed

Conditions: Complex Regional Pain Syndromes

Treatments: Other: Multimodal rehabilitation

Study type: Interventional

Funder types: NETWORK

Identifiers

NCT05696587

STATUT 2020

Details and patient eligibility

About

The goal of this clinical trial is to learn about cognitive changes during rehabilitation in CRPS patients. The main questions it aims to answer are:

• What are the cognitive changes in CRPS?
• Do cognitive functions change during multimodal rehabilitation in CRPS?
• What is the effect of multimodal rehabilitation on pain, functioning, mood, active range of motion, cognitive functions.

Participants will undergo a 4-week program of multimodal rehabilitation of physical therapy, education and Graded Motor Imagery. Assessment will be made at baseline and after 4 weeks.

Researchers will compare the interventional arm with healthy control to see if the observed psychological results are exclusive to CRPS group.

There is no expanded access scheduled for this study.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of CRPS (or equivalent);
• MMSE >24 points;
• Has signed an informed consent to the study.

Exclusion criteria

• MMSE ≤24 points;
• Inability to perform scheduled tasks (multimodal rehabilitation program).

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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42 participants in 2 patient groups

CRPS

Experimental group

Description:

Participants meeting inclusion and exclusion criteria undergoing 4-week multimodal rehabilitation, undergoing assessment at baseline and at 4 weeks.

Treatment:

Other: Multimodal rehabilitation

Healthy Control

No Intervention group

Description:

Participants matched according to sex, age and education to experimental arm, undergoing psychological assessment at baseline and at 4 weeks.