Physical Condition in Lipedema and Obesity

Nij Smellinghe Hosptial

Status: Completed

Conditions: Obesity; Lipoedema

Treatments: Other: volume, muscle strength, physical condition, BMI

Study type: Interventional

Funder types: Other

Identifiers

NCT01759004

Nij Smellinghe hospital (Other Identifier)

NS4NL

Details and patient eligibility

About

The diagnosis of lipoedema and obesity are often mixed up, unclear stated and often there is a misdiagnosis. The primary aim is to investigate whether there is a difference in muscle strength between women with lipedema and women with obesity. The secondary aim is to investigate whether there is a difference in physical fitness between women with lipedema and women with obesity.

Full description

Lipedema is a genetically mediated disorder of adipose tissue that occurs exclusively in women. Lipedema is an under-recognized condition, often misdiagnosed as lymfedema or dismissed as simple obesity. The diagnosis of lipedema is a clinical diagnosis and may be challenging to determine among patients who are obese. Measurements of muscle strength and physical fitness may give more clarity to differentiate between lipedema and obesity. This may lead to improvements in the criteria of diagnosing lipedema. The research question of the study is: Is there a difference in muscle strength between adult women with lipedema and adult women with obesity?

In this study 40 patients will be studied; 20 patients in every group. Besides the general data as length, weight, age, abdominal circumference, volume of the legs additional muscle strength and physical fitness of women with lipedema and women with obesity will be measured and analysis.

This study doesn't involve a negligible risk for participants. The study will not have direct benefit for the participants, but may be useful in giving more clarity in defining the phenotype for patients with lipedema.

Enrollment: 40 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

Lipedema group:

• diagnosed with lipedema following the criteria of Wold et al3
• women
• age ≥ 18 years

Obesity group:

• BMI ≥ 30
• women
• age ≥ 18 years

Exclusion criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

Lipedema group:

• none

Obesity group:

• an obesity intervention with physical training in the ≤12 months prior to the measurement

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

patient with lipoedema

Active Comparator group

Description:

Lipedema group: * diagnosed with lipedema following the criteria of Wold * women * age ≥ 18 years clinimetrics: volume, muscle strength, physical condition, BMI

Treatment:

Other: volume, muscle strength, physical condition, BMI

patients with obesity

Active Comparator group

Description:

Obesity group: * BMI ≥ 30 * women * age ≥ 18 years clinimetrics: volume, muscle strength, physical condition, BMI

Treatment:

Other: volume, muscle strength, physical condition, BMI