Physical Exercise for Treatment of Depression and Anxiety - RCT (FYPO)

Region Örebro County

Status: Active, not recruiting

Conditions: Depression; Anxiety

Treatments: Other: Relaxation Therapy; Other: Physical Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT04714528

273723

Details and patient eligibility

About

In a 12 week randomly controlled open trial 102 participants with symptoms of depression and/or anxiety will be exposed to either aerobic high intensity training (HIT) or relaxation therapy. Cognitive functions, biomarkers, psychiatric symptom scales and physical status will be collected at baseline, after 12 weeks and after a year. Depression and anxiety will be measured twice during the intervention period.

Enrollment: 87 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Score ≥12 on MADRS or score ≥16 on BAI
• Inhabitant i Örebro County, Sweden
• BMI ≥18 kg/m^2

Exclusion criteria

• Diagnosis of chronic psychotic disease or ongoing psychotic episode.
• Ongoing manic state of bipolar disorder
• Severe somatic disease or condition where high intensity exercise is contraindicated
• Difficulty with reading, hearing or understanding the Swedish language

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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87 participants in 2 patient groups

Physical Exercise Group

Active Comparator group

Description:

45 minutes of aerobic, high intensity group training, three times per week during a 12-week period.

Treatment:

Other: Physical Exercise

Relaxation Group

Other group

Description:

45 minutes of relaxation therapy once per week for 12 weeks.

Treatment:

Other: Relaxation Therapy