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Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy (EFA)

L

Lars Bo Andersen

Status and phase

Unknown
Phase 2

Conditions

Epilepsy
Epileptic Seizures
Seizure Disorder
Epilepsia

Treatments

Behavioral: Physical activity

Study type

Interventional

Funder types

Other

Identifiers

NCT01450423
S-20110080

Details and patient eligibility

About

Epilepsy is a chronic neurologic disorder characterized by seizures. Beside seizures people suffering from epilepsy experience several challenges related to education, work and everyday life such as learning-, problem-solving-, memory-, concentration-, attention difficulties and fatigue.

It is generally approved that physical activity (PA) has a positive effect on physical as well as mental factors. However, people with epilepsy are found to be less active and PA is rarely offered or recommended as supplement to anti-epileptic medical treatment. Few studies have investigated the effect of PA in subjects with epilepsy and additional studies of high methodical quality are needed to enable evidence-based information and counselling.

This study is carried through as a randomized controlled trial which investigates the effect of participation in a 10-week cardio exercise program in people with Juvenile Myoclonic Epilepsy aged 15-50.

The study hypothesis is that participation in a 10-week cardio exercise program will induce a positive change in cognitive function (concentration and attention) and possibly in brain-derived neurotrophic factor (BDNF). In addition it is expected that the intensity and duration of the 10-week cardio exercise program is sufficient to cause changes in physiological parameters related to a reduced risk of lifestyle diseases.

Enrollment

40 estimated patients

Sex

All

Ages

15 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age: 15-50
  • Resident: Fyen, Denmark
  • Epileptic syndrome: Juvenile Myoclonic Epilepsy

Exclusion criteria

  • Physical handicaps which complicate participation in physical activity

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

40 participants in 2 patient groups

Physical activity
Experimental group
Treatment:
Behavioral: Physical activity
Control
No Intervention group

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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