Physical Exercise Therapy vs Relaxation in Allogeneic Stem Cell Transplantation (PETRA)

German Cancer Research Center

Status: Completed

Conditions: Allogeneic Stem Cell Transplantation

Treatments: Behavioral: exercise and relaxation

Study type: Interventional

Funder types: Other

Identifiers

NCT01374399

DJCLS R 10/42pf

Details and patient eligibility

About

The PETRA-Study is a randomized, controlled trial and designed to examine the effects of an one-year physical exercise intervention on prognosis, side-effects and complications after allogeneic stem cell transplantation.

The exercise intervention includes both, resistance and endurance training. Patients assigned to the control group perform a relaxation program (progressive muscle relaxation - Jacobsen) and have the same frequency of social contact.

Enrollment: 267 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Medical indication: allogeneic stem cell transplantation

Exclusion criteria

• Orthopeadic limitations that hamper the exercise intervention
• Osseous degenerations that have an improved fracture risk

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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267 participants in 2 patient groups

resistance and endurance exercise

Experimental group

Treatment:

Behavioral: exercise and relaxation

relaxation

Active Comparator group

Treatment:

Behavioral: exercise and relaxation